why do i feel worse after my b12 injection why do i feel worse after my b12 injection

I'm injections for 2 months now, my GP and GI still refuse to run my blood test saying it is not needed The more injections I get (I started injecting myself every 48 hours 500 mcg hydroxycobalamin because 1000 mcg was unbearable to deal with feeling sick for days) the more pain and symptoms increase. If it is high, it might be worth seeing what your methylmalonic acid (MMA) is doing. Typically, our patients experience positive effects between 24-72 hours after the treatment. I am not a medically trained person but I've had Pernicious Anaemia (one of many causes of B12 deficiency) for more than 50 years. Doctors are now calling the gut "the second brain" so you can imagine all that goes wrong when your villi are decimated and your gut is broken down like it is in those with CD. So all the advice and info we can read here helps to deal with the agony That is true that many doctors arent well educated about this. e u just give it to yourself in the fat of your stomach and it is absolutely painless and that is coming from someone who does not like needles i was terrified but after they administered my first shot at my first appointment it was not bad at all. After all, if you haven't ever seen this result, neither have they. I have pernicious anemia is that what u have too? That is signalling something is wrong, despite blood results being good/erroneous. August 21, 2022 by Sandra Hearth. Fortunately she immediately started her on loading doses and has given her a prescription for B12 for self injection as she needs it. These cookies will be stored in your browser only with your consent. I dont think my actual iron levels are low and the doctor said that I am not anaemic. The eczema story is interesting too! Anyone at any age, can become B12 deficient. What is the , It raises the risk for heart disease, cancer, liver damage, and stroke. Some of those symptoms you mention also track to thyroid issues. A few symptoms of B12 deficiency include: Conditions of the small intestine (Crohns disease), anemia, fatigue, constipation, poor balance, memory loss, shortness of breath, and more. You may experience severe side effects like: Confusion Dizziness Extreme tiredness this seems to be quit good, has good results already, and is easy to tak. I just feel like rubbish all the time and I dont know what to do. B12 is 659pg/mL and folate is the same (this was 4 days after my most recent injection), also taking a B-complex vitamin daily with 15mcg of b12 . The author of the study, Dr. Rosa Caballero, said that the allergens involved in vitamin B12 reactions is likely to be a hapten.. Call your doctor at once if you have: heart problems--swelling, rapid weight gain, feeling short of breath; fluid build-up in All rights reserved. I just had my first shot after the loading doses three days ago. Extreme muscle pains, tingling, tinnitus, dizziness, fatigue, twitching, cramps, actually often feel like I have the flu but no fever. Ive also experienced prolonged pains in my upper left part of my stomach, which happens every so often. Zero cases. This cookie is set by GDPR Cookie Consent plugin. This maybe useful if you have a carer or a family member willing to administer your injection. Thereafter, 100 mcg should be injected once a month for life. We charge as little as $3. WebThis causes symptoms like muscle weakness, fatigue, appetite loss, feelings of unwellness, irritability, numbness, etc. So Im about to go for my first injection (as I have them once every 3 months). I only got a breakthrough with this one doctor who said that I needed a blood test. Thanks. Symptoms. Some symptoms will "disappear" quite quickly whereas others may take months or even years. Also I was severely iron dificient. A one-ounce portion (roughly a quarter cup) of raw . Heres a case of two female pernicious anemia patients who had negative reactions to hydroxy B12 shots. Like it needs to be sorted because its affecting my everyday life. respect of any healthcare matters. Im a lot more out of breath and experiencing dizziness. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Many people experience this issue, yet it is often misunderstood. Why are beauticians giving B-12 injections? Chills, night sweats, fever, or hot flushes. I was fine until I took the shot, afterwards, it had caused mental changes as well as mood changes. Within in a couple of months her eczema was completely gone. Its the one that begins with an H (I cant spell it). ?ve noticed a metallic taste after my injection. How long does 600mg edible last in your system? Then I got a cold and I havent been the same since. I was on prescribed folate but when that finished I now take a multi vitamin every day . It really means a lot that people are so helpful, it really does make a difference in all of this. I personally usually advise people to stick to RDA level vitamins and if they want to go higher with B6 (based on labs), to stay under 10mg which I still think is a reasonable level of caution considering all the evidence. this seems to be quit good, has good results already, and is easy to take u just give it to yourself in the fat of your stomach and it is absolutely painless and that is coming from someone who does not like needles i was terrified but after they administered my first shot at my first appointment it was not bad at all.Read More Read Less, Routine test showed a B12 deficiency that was unreadable by local labs. https://patient.info/forums/discuss/b12-injection-side-effects-512107. Step 1. Hang in there it will get better. Im just worried that these symptoms may be because of the injections or something serious. Things I notice: more energy, improved stamina at the gym and on the field, increased appetite, results from workouts improving, mood improved, restful sleep, and I have lost a few pounds and kept it off easily. And the B12 should help as well. That means any excess is quickly flushed out through the urine. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". I too suggest you make sure your iron levels are ok and also maybe ask for your throid functions to be checked if you havent had that done. I sometimes liken it to a badly tuned radio on which you have turned the volume up high trying to catch the programme you want when all of a sudden the signal comes in loud and clear and the blast nearly deafens you. I was told my energy level would increase and B12 would help prevent dementia. PA testing only picks up 50% of yhise with it. I have a day where I feel ok and then a day where everything seems to start up again. Vitamin B12 injections can cause issues with: Leg pain Muscle pain Muscle weakness Swelling in arms and lower extremities Swelling or pain in one leg Unstable walking Neurological Effects The neurological effects of vitamin B12 affect your brain. After 9 months of feeling completely not myself, test for all sorts of different things plus fighting the " your symptomsare anxiety" card I was finally diagnosed with Coelliac disease and the the B12. People who undergo surgeries or dental procedures involving nitrous oxide, or who use the drug recreationally. H2 blockers, antacids, Metformin, and related diabetes drugs, or other medications, or infections such as h I get tired and short tempered. If you get the blood results Im sure that will help. Was she anaemic? Anyways, I hope you get better!! However, it may take a few days or weeks before your symptoms start to improve and you feel better. Its tough. Id be interested to know how you get on. Brace yourself for the worst right now, but know that each jab and each GF day is making you better! Cant have everything I suppose! So me to currentley struggling to make it through the day. It depends on your progress and how you respond to the injections. Apply a cold compress. All rights reserved. I thought I would feel better straight away, but I suspect Ive been low for years, and so it make sense that recovery might take time! I do recognise some of those symptoms but previous to being diagnosed I had a Thyroiditis and a bang on the head thru a collapse (now have pacemaker). Sandra Hearth is the creator and writer behind "Wellbeing Port", a blog dedicated to promoting healthy living and personal wellness. Sadly my much improved digestion has gone downhill again. Vitamin B12, for example, should definitely be taken in the morning. Thank you about the insight into eczema - mine cleared up too after it getting really bad for the last two years despite medication galore - after two B12 jabs its completely cleared. She told me that many patients tell her they feel tired as they get nearer to their B12 shot been due. I wouldn't want either and I feel for you with both As mentioned already, CD can go with other conditions such as thyroid, PA (low b12 can be fixed, PA requires ongoing supplements/treatment), even type 1 diabetes and other auto-immune conditions. Though rare, this reaction can cause muscle cramping, y in life hysterectomy. hope this answer is helpful. But I feel like I could try it in the next couple of weeks. Mild diarrhea and/or upset stomach. It's my first time to take vitamin B12 in liquid form, but it's easier to eat and absorbs better than I thought. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Untreated B12 deficiency is potentially life-threatening. I have heard of people being told on this forum that their results were "below measurable" -but never that they were non-existant ! The original poster's symptoms sound like normal B12 neurological recovery symptoms to me - similar to those experienced by me and many others here. It is not uncommon for some symptoms to appear to get worse before they get better as the B12 you are having starts repairing the damage done to your nervous system and your brain starts getting multiple messages from part of the body it had "forgotten about" or lost contact with. All our partner labs hold UKAS, ISO17025 / ISO15189 / IS013485 accreditations. HOW dO I SELF-INJECT VITAMIN B12? An abnormal increase in red Try our Symptom Checker Got any other symptoms? Some or all of it can be reversed and that's the good news. This will help your body adjust to the increased levels of B12 without having an adverse reaction. My guess still remains that there's been an error in the process somewhere and it's 'crept out'. For them, it can make things worse. If you have the time and energy, I suggest you search online for any regional or national guidelines for treatment of B12 deficiency. B12 Deficiency is Serious Had I not gotten a third opinion, my situation could have potentially gotten worse. I can't see any blood test results for iron eg ferritin or any other iron tests. WebThis may be affected by the dose and rate of administration. How soon do you feel less tired after a B12 injection? However, we have never had anyone come back to us with an allergic reaction to our B12. Pretty dubious. hope this answer is helpful. Though rare, this reaction can cause muscle cramping, extreme fatigue, and an irregular heartbeat. I learnt a lot about this condition on the Facebook pernicious anemia/b12 deficiency group. Most documentation papers indicate you might experience any of these: However, people fail to recognize one thing. WebI began B-12 injections 2 times per week and within one week noticed a dramatic improvement in my energy levels. So, it's more noticable? The larger-gauge needle is finer than the 22 and will provide the most comfort during the injection. My sister feels like I complain too much, but she's not in our shoes and she wants sympathy-likes on FB if she's got a hangnail. I started B12 injections in March 2009 monthly. The cost for Vitamin B12 injectable solution (1000 mcg/mL) is around $90 for a supply of 25 milliliters, depending on the pharmacy you visit. Without sufficient B12, nerves become exposed and are easily damaged resulting in sensory and motor dysfunction. By starting with small doses and gradually increasing them over time, drinking plenty of water both before and after the shots, and getting adequate rest, you can reduce or even eliminate any negative reactions you may experience from taking a B12 injection. Given the vital roles that vitamin B12 plays in your body, a deficiency can have serious health consequences. In fact, low blood levels of the vitamin have been linked to several health problems. Low levels of vitamin B12 have been linked to a decline in brain function. The easiest site when self-administering an IM injection is the middle third of the vastus lateralis muscle of the thigh. But I dont think it is anxiety. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. And the medicines i take may have interferred with it is my only guess as to why this happened. Infections may also occur. These results are really 'quite strange'. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Generalized pain, including arthritis, back pain and muscle pain may occur after a vitamin B12 injection. You also have the option to opt-out of these cookies. Initially, replacing B12 will lead to a huge increase in the production of blood cells and platelets (which occurs in the bone marrow) and can lead to rapid depletion of folate and iron stores; this can then limit the expected recovery of Haemoglobin. If you search online for "Sally Pacholok B12 conference" it should show a link to a slideshow Sally presented to a conference in US. People may lose patience as you sort it all out, but take all the time you need to stay well. Heart palpitations: this could be anxiety - one of the many symptoms of B12 deficiency. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. It's important to stick to your b12 schedule . If possible take someone with you who can validate your neurological symptoms as the doctor is less likely to pooh pooh you in front of a witness. You have both. How are you managing things now, Diagnosis with PA a month ago & had my 6 loading injections last one last week, Feel awful too , worse my b12 was 150 & serum iron 8, Also now started, really hope things improve soon. My general practitioner said to get back on the shots after a couple of years of my not taking them. Avoid irritated skin and blood vessels. The sudden rush of energy can be overwhelming for some people, leading to fatigue and headaches that last for several days after the injection. I will update and let you know how I get on. Generally, the results of vitamin B12 injections can last about one week, but it is vital to have this administered by a healthcare provider. Parasites among the long list thst csn inpede b12 absorbtion . Basically by pervious B12 deifciency symptoms just mych more intense. Important: Patients withLeberhereditary optic neuropathy should not take methyl B12shots. Ive been to a few and none of them can tell me anything. Its quite scary this whole b12 thing. MMA should drop once B12 is replete. Unfortunately, many never receive a root cause diagnosis for various reasons including the poor quality of tests for pernicious anemia, the incompetence and/or disinterest of many doctors in looking for a cause for the deficiency etc. Rhinitis (chronic sneezing or a congested, drippy nose). 6 years ago, I have B6 toxicity, P.A. Eating bananas and trying a very healthy diet but the increase of symptoms and pain make me very, very insecure and scared. Regular provision of intravenous B12 in such circumstances is necessary for the continuation of life - its not a band-aid. If you were a recovering alcholic, you'd have withdrawl symptoms, right? Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Still tired, but better. I feel like I can set myself a realistic expectation for my treatment now. I was found to have "ventricular ectopics" - which, although I had 4,000 episodes in that period, was not dangerous and went away eventually a few months later without needing treatment. At this point, I have not finished my monthly injections and do not plan on doing so. I would respectfully ask if the B12 test could be repeated, I have learned here that B12 supplementing can alter folate levels so I wonder if your folate level being considerably above the high end of the range has masked your B12 deficiency and affected your B12 levels? Whether its a mild rash, a cut, or an eczema flare irritated skin is inflamed and more likely to have a reaction. After an hour after each injection I've felt absolutely exhausted and Hello! i will post further progress with this drug as my treatment furthers with it. : An Epidemic of Misdiagnoses" by Sally Pacholok and JJ. Good luck and I wish you well on your recovery xxx. Hypophosphatemia after an iron infusion is quite rare. H2 blockers, antacids, Metformin, and related diabetes drugs, or other medications, or infections such as h-pylori that can interfere with B12 absorption. A retest now of serum B12, once on weekly injections, will probably be unhelpful as it will be high either way. However, certain people are at an elevated risk. I chose high-efficiency lysoformal because it's the trending vitamin these days, so I think it's better than other B vitamins. I had plenty of this. If anything other than sterile saline was added, it may have been a preservative that you had reacted to. I have seen previous comments regarding successful weight loss, but this has not been my experience (even with diet and daily exercise). It does get better, just make sure you get the next 2 or 3 monthly top up jabsI've had to pay privately for mine as nhs seem to think a reading of 305 is okwhen it's defiantly not. cystic acne breakouts by a dermatologist. I have MTHFR mutation and wonder if this might be why they are not having a good effect on me. I can't say since your gut is healing at the same timeBut as someone who had a rollercoaster in a smaller way, I can tell you that B12 is your friend and you will feel better. Next link about causes is from a Dutch B12 website. I feel the same I don't feel any better my doctor thinks it's in my head as I should feel so much better I feel soow, How are you feeling now? What are the signs and symptoms of a vitamin B12 deficiency? The best way to prevent feeling worse after a B12 injection is by starting with small doses and gradually increasing them over time. You would have to be repeatedly going above the tolerable upper intake limit every day for quite a long time before you would run into issues. I am going back to review my labs in person soon with my GP and not sure the approach I should take on how to convince him to check other things and what other things should be looked at. Avoid strenuous exercise for 48 hours after your treatment. I don't doubt in the least that juanpablo is suffering from something, but I'd be surprised if B12 had anything to do with it. Tingling, numbness, weakness, and balance problems. Vitamin B-12 is a water-soluble B complex vitamin found naturally in a variety of foods, including meat, fish and dairy products. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12. If you get b12 shots, you may experience side effects like dizziness, nausea, and fatigue. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Sally Pacholok has written some online articles about B12 deficiency which may be worth searching for. Some patients do feel worse before they get better. Oddly, she had been battling a pretty severe case of eczema which disappeared after she started getting B12 shots. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. received my 6 shots of B12. Its supposed to check my calcium levels, iron levels, and to see if theres any inflammation in my stomach +other things. I dont get them symptoms as much anymore, I still get foot cramps every so often and I have numbness in my left leg and left hand. Vitamin B-12 injections or nasal spray might be prescribed to treat vitamin B-12 deficiency. Feeling worse after B12 Injections. I never read on the B-12 shot, but I received it yesterday at,12:30 pm and around 5 this morning I started with belly pain and diarrhea.